animaApproximateMCMSmoothingCostFunction.h

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#pragma once

#include <itkSingleValuedCostFunction.h>
#include <AnimaMCMSimilarityExport.h>
#include <animaMultiCompartmentModel.h>
#include <animaMCMConstants.h>

namespace anima
{

class ANIMAMCMSIMILARITY_EXPORT ApproximateMCMSmoothingCostFunction : public itk::SingleValuedCostFunction
{
public:
    typedef ApproximateMCMSmoothingCostFunction Self;
    typedef itk::SingleValuedCostFunction Superclass;
    typedef itk::SmartPointer<Self> Pointer;
    typedef itk::SmartPointer<const Self> ConstPointer;

    itkNewMacro(Self)

    
    itkTypeMacro(ApproximateMCMSmoothingCostFunction, itk::SingleValuedCostFunction)

    typedef Superclass::MeasureType MeasureType;
    typedef Superclass::DerivativeType DerivativeType;
    typedef Superclass::ParametersType ParametersType;

    typedef anima::MultiCompartmentModel MCModelType;
    typedef MCModelType::Pointer MCMPointer;
    typedef MCModelType::Vector3DType GradientType;
    typedef anima::BaseCompartment::Pointer BaseCompartmentPointer;
    typedef anima::BaseCompartment::Vector3DType Vector3DType;

    virtual MeasureType GetValue(const ParametersType &parameters) const ITK_OVERRIDE;
    virtual void GetDerivative(const ParametersType &parameters, DerivativeType &derivative) const ITK_OVERRIDE;

    void SetReferenceModels(const std::vector <MCMPointer> &refModels, const std::vector <GradientType> &gradients,
                            const double &smallDelta, const double &bigDelta, const std::vector <double> &gradientStrengths);
    void SetMovingModels(const std::vector<MCMPointer> &movingModels, const std::vector <GradientType> &gradients,
                         const double &smallDelta, const double &bigDelta, const std::vector <double> &gradientStrengths);

    void SetGradientStrengths(const std::vector <double> &val);
    void SetGradientDirections(const std::vector <GradientType> &val);

    void SetBValueWeightIndexes(const std::vector <unsigned int> &val);
    void SetSphereWeights(const std::vector <double> &val);

    itkSetMacro(ParameterScale, double)
    void SetSmallDelta(double val);
    void SetBigDelta(double val);

    unsigned int GetNumberOfParameters() const ITK_OVERRIDE {return 1;}

protected:
    ApproximateMCMSmoothingCostFunction()
    {
        m_UpdatedData = false;
        m_ConstantTerm = 0;
        m_ParameterScale = 1.0e-3;
        m_SmallDelta = anima::DiffusionSmallDelta;
        m_BigDelta = anima::DiffusionBigDelta;
    }

    virtual ~ApproximateMCMSmoothingCostFunction() {}

private:
    ApproximateMCMSmoothingCostFunction(const Self&); //purposely not implemented
    void operator=(const Self&); //purposely not implemented

    std::vector < std::vector <double> > m_ReferenceModelSignalValues;
    std::vector < std::vector <double> > m_MovingModelSignalValues;

    std::vector <unsigned int> m_BValueWeightIndexes;
    std::vector <double> m_GradientStrengths, m_SphereWeights;
    std::vector <GradientType> m_GradientDirections;

    mutable bool m_UpdatedData;
    mutable double m_ConstantTerm;
    double m_ParameterScale;
    double m_SmallDelta, m_BigDelta;
};

} // end namespace anima